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P. Jeffrey Conn, Craig W. Lindsley, Jens Meiler, Colleen M. Niswender
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| Opportunities and challenges in the discovery of allosteric modulators of GPCRs for treating CNS disorders |
| Nature Reviews Drug Discovery |
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Huixian Wu, Chong Wang, Karen J. Gregory, Gye Won Han, Hyekyung P. Cho, Yan Xia, Colleen M. Niswender, Vsevolod Katritch, Jens Meiler, Vadim Cherezov, P. Jeffrey Conn, Raymond C. Stevens
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| Structure of a Class C GPCR Metabotropic Glutamate Receptor 1 Bound to an Allosteric Modulator |
| Science |
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Holger Jaeschke, Joerg Schaarschmidt, Markus Eszlinger, Sandra Huth,
Rudolf Puttinger, Olaf Rittinger, Jens Meiler, Ralf Paschke
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| A newly discovered TSHR variant (L665F) associated with non-autoimmune hyperthyroidism in an Austrian family induces constitutive TSHR activation by steric repulsion between TM1 and TM7 |
| Journal of Clinical Endocrinology & Metabolism |
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Holger Jaeschke, Joerg Schaarschmidt, Markus Eszlinger, Sandra Huth, Rudolf Puttinger, Olaf Rittinger, Jens Meiler, and Ralf Paschke
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| A Newly Discovered TSHR Variant (L665F) Associated With Nonautoimmune Hyperthyroidism in an Austrian Family Induces Constitutive TSHR Activation by Steric Repulsion Between TM1 and TM7 |
| The Journal of Clinical Endocrinology and Metabolism |
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Sandeepkumar Kothiwale, Corina M. Borza, Edward W. Lowe Jr,
Ambra Pozzi and Jens Meiler
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| Discoidin domain receptor 1 (DDR1) kinase as target for structure-based drug discovery |
| Drug Discovery Today |
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Kevin K. Kumar, Edward W. Lowe, Jr., Asad A. Aboud, M. Diana Neely, Rey Redha,
Joshua A. Bauer,Mihir Odak, C. David Weaver, Jens Meiler, Michael Aschner, Aaron B. Bowman
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| Cellular manganese content is developmentally regulated in human dopaminergic neurons |
| Scientific Reports |
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Ali I Kaya, Alyssa D. Lokits, James A. Gilbert, Tina M. Iverson, Jens Meiler, Heidi E. Hamm
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| A conserved phenylalanine as a relay between the α5 helix and the GDP binding region of heterotrimeric Gi protein α subunit |
| Journal of Biological Chemistry |
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Xavier Pedragosa-Badia, Gregory R. Sliwoski, Elizabeth Dong Nguyen, Diana Lindner, Jan Stichel, Kristian W. Kaufmann, Jens Meiler
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| Pancreatic Polypeptide Is Recognized by Two Hydrophobic Domains of the Human Y4 Receptor Binding Pocket |
| Journal of Biological Chemistry |
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John P. Donahue, Rebecca T. Levinson, Jonathan H. Sheehan, Lorraine Sutton, Harry E. Taylor, Jens Meiler, Richard T. D'Aquila, Chisu Song
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| Genetic Analysis of the Localization of APOBEC3F to Human Immunodeficiency Virus Type 1 (HIV-1) Virion Cores |
| Journal of Virology |
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Claudia Doberenz, Michael Zorn, Dörte Falke, David Nannemann, Doreen Hunger, Lydia Beyer, Christian H. Ihling, Jens Meiler, Andrea Sinz, R. Gary Sawers
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| Pyruvate Formate-Lyase Interacts Directly with the Formate Channel FocA to Regulate Formate Translocation |
| Journal of Molecular Biology |
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Karen Joan Gregory, Elizabeth D Nguyen, Chrysa Malosh, Jeffrey L Mendenhall, Jessica Z Zic, Brittney S Bates, Meredith J Noetzel, Emma F Squire, Eric M Turner, Jerri M. Rook, Kyle A Emmitte, Shaun R. Stauffer, Craig W Lindsley, Jens Meiler, and P. Jeffrey Conn
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| Identification of specific ligand-receptor interactions that govern binding and cooperativity of diverse modulators to a common metabotropic glutamate receptor 5 allosteric site |
| ACS Chemical Neuroscience |
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Philip Lossl, Knut Ko¨lbel, Dirk Ta¨nzler, David Nannemann, Christian H. Ihling, Manuel V. Keller, Marian Schneider, Frank Zaucke, Jens Meiler, Andrea Sinz
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| Analysis of Nidogen-1/Laminin γ1 Interaction by Cross-Linking, Mass Spectrometry, and Computational Modeling Reveals Multiple Binding Modes |
| PLOSOne |
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Aleksandra Margeti?, David Nannemann, Jens Meiler, Daniel Huster, Stephan Theisgen
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| Guanylate Cyclase-Activating Protein-2 Undergoes Structural Changes upon Binding to Detergent Micelles and Bicelles |
| Biochimica et Biophysica Acta (BBA) - Biomembranes |
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Thomas Austin, David P. Nannemann, Sam DeLuca, Jens Meiler, Eric Delpire
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| In silico Analysis and Experimental Verification of OSR1 Kinase - Peptide Interaction |
| Journal of Structural Biology |
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Kathleen F. Mittendorf, Brett M. Kroncke, Jens Meiler, Charles R. Sanders
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| The Homology Model of PMP22 Suggests Mutations Resulting in Peripheral Neuropathy Disrupt Transmembrane Helix Packing |
| Biochemistry |
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Veronika Made, Dr. Kathrin Bellmann-Sickert, Anette Kaiser, Prof.?Dr. Jens Meiler, Prof.?Dr. Annette G. Beck-Sickinger
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| Position and Length of Fatty Acids Strongly Affect Receptor Selectivity Pattern of Human Pancreatic Polypeptide Analogues |
| ChemMedChem |
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Van Hoveln, R. J., Schmid, S. C.; Tretbar, M.; Buttke, C.; Schomaker, J. M.
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| Formal Asymmetric Hydrobromination of Styrenes via Copper-Catalyzed 1,3-Halogen Migration |
| Chemical Science |
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Alexander Sevy, Jens Meiler
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| Antibodies: Computer-Aided Prediction of Structure and Design of Function |
| Microbiology Spectrum |
