• Chemical Shift Prediction
• Jufo9D Secondary Structure and TM Span Prediction
• Method Development for QSAR Ligand-based Virtual Screening

Kaufmann K.;Glab K., Mueller R., Meiler J.
Small Molecule Rotamers Enable Simultaneous Optimization of Small Molecule and Protein Degrees of Freedom in ROSETTALIGAND Docking (2008) German Conference on Bioinformatics

Koehler, J.;Mueller, R., Meiler, J.
Improved prediction of trans-membrane spans in proteins using an Artificial Neural Network (best overall student paper in IEEE symposium) (2009) In IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology; Wiese

Butkiewicz, M.;Mueller, R., Selic, D., Dawson, E., Meiler, J.
Application of Machine Learning Approaches on Quantitative Structure Activity Relationships (best student paper in IEEE symposium in CIBCB) (2009) In IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology; Wiese

Mueller, R.;Rodriguez, A. L.; Dawson, E. S.; Butkiewicz, M.; Nguyen, T. T.; Oleszkiewicz, S.; Bleckmann, A.; Weaver, C. D.; Lindsley, C. W.; Conn, P. J.; Meiler, J.
Identification of Metabotropic Glutamate Receptor Subtype 5 Potentiators Using Virtual High-Throughput Screening (2010) ACS Chemical Neuroscience

Ralf Mueller;Eric S. Dawson, Jens Meiler, Alice L. Rodriguez, Brian A. Chauder, Brittney S. Bates, Andrew S. Felts, Jeffrey P. Lamb, Usha N. Menon, Sataywan B. Jadhav, Alexander S. Kane, Carrie K. Jones, Karen J. Gregory, Colleen M. Niswender, P. Jeffrey Conn, Christopher M. Olsen, Danny G. Winder, Kyle A. Emmitte, Craig W. Lindsley
Discovery of 2-(2-Benzoxazoyl amino)-4 Aryl-5-Cyanopyrimidine as Negative Allosteric Modulators (NAMs) of Metabotropic Glutamate Receptor 5 (mGlu5): From an Artificial Neural Network Virtual Screen to an In Vivo Tool Compound (2012) ChemMedChem

Ralf Mueller;Eric S. Dawson, Colleen M. Niswender, Mariusz Butkiewicz, Corey R. Hopkins, C. David Weaver, Craig W. Lindsley, P. Jeffrey Conn, Jens Meiler
Iterative experimental and virtual high-throughput screening identifies metabotropic glutamate receptor subtype 4 positive allosteric modulators (2012) J Mol Model

Nils Woetzel;Mert KarakaS, Rene Staritzbichler, Ralf Mueller, Brian E. Weiner, Jens Meiler
BCL::Score-Knowledge Based Energy Potentials for Ranking Protein Models Represented by Idealized Secondary Structure Elements (2012) PLOS One

Butkiewicz M;Lowe EW, Mueller R, Mendenhall JL, Teixeira PL, Weaver CD, Meiler J.
Benchmarking Ligand-Based Virtual High-Throughput Screening with the PubChem Database (2013) Molecules

Julia Koehler Leman;Ralf Mueller, Mert Karakas, Nils Woetzel, Jens Meiler
Simultaneous prediction of protein secondary structure and transmembrane spans (2013) Proteins

Julia Koehler;Ralf Mueller, and Jens Meiler
Improved prediction of trans-membrane spans in proteins using an Artificial Neural Network (2009) Computational Intelligence in Bioinformatics and Computational Biology (CIBCB), IEEE Symposium