Group Members


Laura Friggeri

Current Post-Doctoral Fellow

PhD in Pharmaceutical Sciences, Sapienza University of Rome, Italy
laura.friggeri [ at ]
Vanderbilt University - MBRIII 5140 Office Suite

Research Interests:

  • Small molecule drug discovery
  • Organic synthesis
  • Hit to Lead optimization
  • Structured-based drug design


Collaboration with Prof. Craig W. Lindsley


Project Description:

I am working to develop novel chemotypes targeting allosteric binding pockets of GPCRs, particularly the class C metabotropic glutamate receptors (mGluRs) by combining computational methods such as structure-based computer aided drug discovery (SB-CADD), ligand-based computer aided drug discovery (LB-CADD), and chemical synthesis. Integration of structural models with small molecule structure-activity relationship data can help us identify novel scaffolds with a focus on drug-like properties (solubility, absorption, metabolism, etc.) to be applied to new biological targets.


Publication Link:

  • Research Projects
  • Publications