Group Members

Abdullah Al Mamun

Current Post-Doctoral Fellow

Ph.D. in chemistry, University of Louisville, USA
abdullah.al.mamun [ at ] vanderbilt.edu
Vanderbilt University - MBRIII 5140 Office Suite

Research Interests:

• Translational cancer research
• Biomolecular modeling
• Simulations using MC, MD, QM/MM methods
• Multiscale method development
• QM/MM MC

I am working to understand the effect of different oncogenic mutations in receptor tyrosine kinase (RTK) proteins. RTK plays a vital role in cellular signaling and is mutated in various cancers, including breast and lung cancers. A detailed molecular-level investigation of these mutagenesis effects is crucial for devising effective targeted therapy in cancer treatment. I am also interested in combining quantum mechanics with Rosetta to develop a QM/MM MC multiscale method. The implementation of such a technique in Rosetta is essential for the enzyme design and to understand protein-ligand interactions more effectively.

Publication Link:

https://scholar.google.com/citations?user=d7IiXRUAAAAJ&hl=en